Which medical development for leukemia treatment was made possible by animal research?

Study for the Comprehensive Guide to Animal Use and Care in Biomedical Research Test. Engage with flashcards and multiple choice questions, each with helpful hints and detailed explanations. Prepare thoroughly for your test!

Multiple Choice

Which medical development for leukemia treatment was made possible by animal research?

Explanation:
Animal studies showed that certain chemicals could kill rapidly dividing cells throughout the body, including malignant blood cells, and reach them wherever they reside. In leukemia research, preclinical experiments in animals with leukemia-like disease demonstrated that cytotoxic drugs could shrink disease, improve survival, and establish dosing and scheduling concepts. This solid, demonstrable benefit in animals provided the essential evidence to move these drugs into human trials, making chemotherapy a standard systemic treatment for leukemia. While other options have important roles in medicine, the specific advance made possible by animal research for leukemia treatment is the development of chemotherapy.

Animal studies showed that certain chemicals could kill rapidly dividing cells throughout the body, including malignant blood cells, and reach them wherever they reside. In leukemia research, preclinical experiments in animals with leukemia-like disease demonstrated that cytotoxic drugs could shrink disease, improve survival, and establish dosing and scheduling concepts. This solid, demonstrable benefit in animals provided the essential evidence to move these drugs into human trials, making chemotherapy a standard systemic treatment for leukemia. While other options have important roles in medicine, the specific advance made possible by animal research for leukemia treatment is the development of chemotherapy.

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